Date of Award
University or Center
Atlanta University (AU)
Dr. George E. Riley
This study was undertaken to determine what effect thyroxin would have on metabolic responses of male Long-Evans rats subjected to low environmental temperatures. Animals were subjected to ambient temperatures of 26 C, 18 C and 10 C for short durations of time and were subcutaneously injected with thyroxin (2 mg per kg body weight) in a physiological saline solution. Calculations based on the data presented indicates that at 26 C, thyroxin had the greatest effect on the volume and rate of oxygen consumed. The animals, however, consumed more oxygen at 18 C and 10 C, but the temperature, endogenous and exogenous thyroxin seemed to have been factors responsible for this great increase in oxygen consumption.
It was concluded that thyroxin, when administered to rats, is involved in the role of thermoregulation and the ultimate effect would depend on the ambient temperature.
Twiggs, Rosco, "The effects of throxin on metabolic responses of male rats subjected to low temperatures" (1967). ETD Collection for AUC Robert W. Woodruff Library. 1678.