A study of the glomerular filtration rate and urine output in renal ischemic sprague-dawley rats, 1978
Middleton, Stewart
1970-1979
This investigation was conducted to measure the glomerular filtration rate (GFR) and urine output of one-kidney Goldblatt (1-kG) and two-kidney Goldblatt (2-kG) renal ischemic Sprague-Dawley rats. Renal ischemia was produced by partial constriction of the left renal artery with a silver clip and removing the contralateral kidney (1-kG) or leaving the contralateral kidney intact (2-kG). Results showed that the 1-kG and 2-kG experimental rats GFRs and urine output were less than their respective controls. Variations in these results were produced as a result of internal factors of the ischemic kidneys, mainly a decrease in the number of glomeruli, the total surface area of glomerular membrane and the filtration pressure of glomerular capillaries.
text
application/pdf
1978-08-01
thesis
Master of Science (MS)
Atlanta University
Department of Biology
Myers, Joseph B.
Clark Atlanta University
Georgia--Atlanta
http://hdl.handle.net/20.500.12322/cau.td:1978_middleton_stewart