Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and ferrocene derivatives through GSH efflux
Coleman, Niwa
2014
2010-2019
There have been many important developments in medicine over the years, but cancer remains a growing problem around the world. This can, to a great extent, be attributed to the growing problem of multi-drug resistance (MDR) of cancer. One strategy for addressing the MDR phenotype is to modulate the activity of the MRP1, an ABC transporters. Therefore, this work seeks to investigate the effects of ferrocene-based compounds on MRP1 mediated cancers that are MDR.
text
application/pdf
conference proceedings
Enhancing Global Research and Education in STEM at Spelman College (G-STEM)
Winfield, Leyte Boumendjel, Ahcene
Spelman College
Georgia--Atlanta
http://hdl.handle.net/20.500.12322/sc.gstem:2014_coleman_niwa
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